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Phenobarbital oral dosing

Weight	(kg)
	Patient aged 4-12yrs
Target Steady state	(mg/L) {range 15-40}
Current steady state	(mg/L) {used for top-up loading doses}

Preferred dosing frequency

Loading Dose	(mg)
Maintenaince Dose	(mg/day)

Calculation(s) used

Vd = n x LBW (Kg)
where n = 0.9 L/Kg {neonates}, n=0.7 L/kg {children and adults}
Cl = 0.1 L/Kg/day {adults and neonates}, Cl= 0.2 L/Kg/day {children}

Notes

References
1. Winter, M.E., (2004). Basic clinical pharmacokinetics. London: Lippincott, Williams and Williams.

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