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  Phenobarbital oral dosing  

Weight (kg)
  Patient aged 4-12yrs  
Target Steady state (mg/L) {range 15-40}
Current steady state (mg/L)
{used for top-up loading doses}
Preferred dosing frequency
Loading Dose (mg)
Maintenaince Dose (mg/day)

Calculation(s) used

Vd = n x LBW (Kg)
where n = 0.9 L/Kg {neonates}, n=0.7 L/kg {children and adults}
Cl = 0.1 L/Kg/day {adults and neonates}, Cl= 0.2 L/Kg/day {children}



1. Winter, M.E., (2004). Basic clinical pharmacokinetics. London: Lippincott, Williams and Williams.

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