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Digoxin oral dosing
IBW
(kg)
Creatinine Clearance
(mL/min)
Heart Failure
Target steady state
(ng/mL) {Range: 1-2}
Current steady state
(ng/mL)
{ used for top-up loading doses }
Preferred dosing frequency
o.d. (once daily)
b.d. (twice daily)
t.d. (three times daily)
q.d. (four times daily)
Loading Dose
(mcg) { in divided doses}
Maintenance Dose
(mcg/day)
Calculation(s) used
Digoxin
References
1. Winter, M.E., (2004).
Basic clinical pharmacokinetics
. London: Lippincott, Williams and Williams.
2. Clinical Pharmacokinetics – Soraya Dhillon and Andrzej Kotstrzewski
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Jamie Alnasir
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